Entries by Lydia Lynch

Metabolic reprogramming of natural killer cells in obesity limits anti-tumor responses

A recent publication by the Lynch Lab on how cancer-fighting natural killer cells are inactivated during obesity has been picked up by several news outlets! Well done guys! Here are a few links below: https://www.independent.ie/irish-news/health/trinity-college-scientists-discover-new-link-between-obesity-and-cancer-37519901.html https://www.irishmirror.ie/news/irish-news/health-news/irish-scientists-trinity-college-dublin-13578617 https://www.thejournal.ie/cancer-obesity-research-trinity-college-dublin-4335526-Nov2018/ https://www.irishexaminer.com/breakingnews/views/ourview/fighting-obesity-and-cancer–kitchen-class-884929.html

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes.

Hong, S. and Song, W. and Zushin, P.-J.H. and Liu, B. and Jedrychowski, M.P. and Mina, A.I. and Deng, Z. and Cabarkapa, D. and Hall, J.A. and Palmer, C.J. and Aliakbarian, H. and Szpyt, J. and Gygi, S.P. and Tavakkoli, A. and Lynch, L. and Perrimon, N. and Banks, A.S. Phosphorylation of Beta-3 adrenergic receptor at […]

NK cell cartoon

Thank you Pedromics for the cartoon based on our recent paper in ‘Nature Immunology’ – “Metabolic Reprogramming of Natural Killer cells in obesity limits anti-tumor responses. Looks great! See it here: https://lynch-lab.org/wp-content/uploads/2018/12/NKCartoon.pdf

Metabolic reprogramming of natural killer cells in obesity limits anti-tumor responses

Xavier Michelet, Lydia Dyck, Andrew Hogan, Roisin M. Loftus, Danielle Duquette, Kevin Wei, Semir Beyaz, Ali Tavakkoli, Cathriona Foley, Raymond Donnelly, Cliona O’Farrelly, Mathilde Raverdeau, Ashley Vernon, William Pettee, Donal O’Shea, Barbara S. Nikolajczyk, Kingston H. G. Mills, Michael B. Brenner,David Finlay & Lynch, L. 2018. Metabolic reprogramming of natural killer cells in obesity limits anti-tumor […]