Diet, nutrient supply, and tumor immune responses

/in /by

McIntyre, C. L., Temesgen, A. & Lynch, L. Diet, nutrient supply, and tumor immune responses. Trends in Cancer, 9, 752–763 (2023) | PubMed

γδ T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors

/in /by

Harmon, Cathal.  Alexandra Zaborowski, Haim Moore, Pamela St. Louis, Karen Slattery, Danielle Duquette, John Scanlan,  Harry Kane, Britta Kunkemoeller, Claire L. McIntyre, Aine Ni Scannail, Bruce Moran, Ana C. Anderson, Des Winter, Donal Brennan, Michael A. Brehm & Lydia Lynch. γδ T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors. Nature Cancer (2023) | PubMed

Interleukin-17 as a key player in neuroimmunometabolism

/in /by

Douglas, A., Stevens, B. & Lynch, L. Interleukin-17 as a key player in neuroimmunometabolism. Nature Metabolism 5, 1088–1100 (2023) | PubMed

Diverse effects of obesity on antitumor immunity and immunotherapy

/in /by

Dyck, L. & Lynch, L. Diverse effects of obesity on antitumor immunity and immunotherapy. Trends in Molecular Medicine 29, 112–123 (2023) | PubMed

γδ T cells unveil invisible tumors

/in /by

Koay, H.-F. & Lynch, L. γδ T cells unveil invisible tumors. Trends in Immunology 44, 159–161 (2023) | PubMed

Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells

/in /by

Kane, H., LaMarche, N. M.,  Ní Scannail, A.,  Garza, A. E., Koay, H. F., Azad, A. I., Kunkemoeller, B., Stevens, B., Brenner, M. B.,  Lynch, L. Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells. eLife 11, e76586 (2022) | PubMed

The therapeutic and prognostic implications of immunobiology in colorectal cancer: a review

/in /by

Zaborowski, A. M., Winter, D. C. & Lynch, L. The therapeutic and prognostic implications of immunobiology in colorectal cancer: a review. Br J Cancer 125, 1341–1349 (2021) | PubMed

Immune and non-immune functions of adipose tissue leukocytes

/in /by

Trim, W. V., & Lynch, L. (2022). Immune and non-immune functions of adipose tissue leukocytes. Nature reviews. Immunology, 22(6), 371–386. | https://pubmed.ncbi.nlm.nih.gov/34741167/

Diet, lipids, and antitumor immunity

/in /by

Prendeville, H., Lynch, L., 2022. Diet, lipids, and antitumor immunity. Cellular & Molecular Immunology, 19, pp. 432–444 | Pubmed

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

/in /by

Lopes, N., McIntyre, C., Martin, S., Raverdeau, M., Sumaria, N., Kohlgruber, A.C., Fiala, G.J., Agudelo, L.Z., Dyck, L., Kane, H., Douglas, A., Cunningham, S., Prendeville, H., Loftus, R., Carmody, C., Pierre, P., Kellis, M., Brenner, M.B., Argüello, R.J., Silva-Santos, B., Pennington, D.J. and Lynch, L., 2021. Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments. Nature Immunology, 22(2), pp.179-192. | PubMed