Adipose Tissue Inflammation in the Pathogenesis of Type 2 Diabetes

A. Kohngruber, and L. Lynch. Adipose Tissue Inflammation in the Pathogenesis of Type 2 Diabetes. Current Diabetes Reports, 2015:15(11):92. | PubMed

Surgical injury induces local and distant adipose tissue browning

A. Longchamp, M. Tao, A. Bartelt, K. Ding, L. Lynch, C. Hine, J. Corpataux, B.S. Kristal, J.R. Mitchell, and C.K. Ozaki. Surgical injury induces local and distant adipose tissue browning. Adipocyte, 2015;5(2):163-174. | PubMed

The transcriptional program of iNKT cells.

E.Y. Kim, L. Lynch, P.J. Brennan, N.R. Cohen, and M.B. Brenner. The transcriptional programs of iNKT cells. Review. Seminars in Immunology, 2015;27(1):26-32. | PubMed

The interplay between the immune system and adipocytes in metabolic control.

M. Exley, D. O’Shea, and L. Lynch. The interplay between the immune system and adipocytes in metabolic control. Invited Review. Journal of Endocrinology, 223:41-48. | PubMed

Adipose invariant Natural Killer T cells

L. Lynch. Adipose invariant Natural Killer T cells. Review. Immunology, 2014;142(3):337-46. | PubMed

Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation.

G.A. Tynan, C. Hearnden, E. Oleszycka, C. Lyons, G. Coutts, J. O’Connell, M. Corrigan, L. Lynch, M. Campbell, JJ. Callanan, K. Mok, J. Geoghegan, C. O’Farrelly, SM. Allan, H. Roche, D. O’Shea, and E. Lavelle. Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation. Diabetes 2014; 63(6):2037-50. | PubMed

Glucagon-like peptide-1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus.

A.E. Hogan, G. Gaoatswe, L. Lynch, M. Corrigan, C. Woods, J. O’Connell and D. O’Shea. Glucagon-like peptide-1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus. Diabetalogica 2014; 57(4):781-4. | PubMed

Adipose Tissue Invariant Natural Killer T Cells Protect Against Diet-Induced Obesity and Metabolic Disorder Through Regulation Cytokine Prodution.

L. Lynch, M. Nowak, B. Varghese, A.E. Hogan, V. Toxavidis, S.P. Balk, D. O’Shea, C. O’Farrelly, and M.A. Exley. Adipose Tissue Invariant Natural Killer T Cells Protect Against Diet-Induced Obesity and Metabolic Disorder Through Regulation Cytokine Prodution. Immunity, 2012; 21;37(3):574-87. | PubMed

Decidual haematopoietic stem cells in first trimester pregnancy.

L. Szereday, E. Miko, M. Meggyes, A. Barakonyi, B. Farkas, J. Bodis, L. Lynch, Cliona O’Farrelly and J. Szekeres-Bartho. Decidual haematopoietic stem cells in first trimester pregnancy. American J Reproductive Immunology 2012; 67(1):9-16. | PubMed

Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: reversing tumor-induced defects [review]. Invited Review: Clinical Applications of NKT cells.

M.A. Exley, L. Lynch, B. Varghese, M. Nowak, N. Alatrakchi, and S. Balk. Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: reversing tumor-induced defects [review]. Invited Review: Clinical Applications of NKT cells Clin Immunol. 2011; 140(2):184-95. | PubMed