Roisin Loftus was recently awarded the Irish Cancer Society 2019 biomedical research fellowship to advance obesity-associated cancer research in Ireland. Recent research from the Lynch lab has shown that obesity blocks the normal functions of Natural Killer cells, which may contribute to the increased risk of cancer in obesity. The focus of Roisin’s ICS fellowship is to investigate how the type of dietary fat we eat differentially shapes the metabolism and function of Natural Killer cells.
Roisin would like to thank the Irish Cancer Society for funding this important research and all the volunteers and supporters for their contributions to help raise awareness about obesity-associated cancers.
A recent publication by the Lynch Lab on how cancer-fighting natural killer cells are inactivated during obesity has been picked up by several news outlets!
Well done guys!
Here are a few links below:
Thank you Pedromics for the cartoon based on our recent paper in ‘Nature Immunology’ – “Metabolic Reprogramming of Natural Killer cells in obesity limits anti-tumor responses. Looks great!
See it here: https://lynch-lab.org/wp-content/uploads/2018/12/NKCartoon.pdf
Congratulations to Dr. Ayano Kohlgruber PhD!
Lydia met with President Michael D. Higgins at the SFI President of Ireland Future Research Leader Awards!
Congratulations to Ayano Kohlgruber on her prize-winning poster ‘Gamma-delta T cells producing IL-17A regulate adipose Treg Homeostasis and thermogenesis‘.
Innate lymphoid cells (ILCs) residing in adipose tissue participate in the pathogenesis of obesity, but their contribution toward adipose tissue homeostasis in the lean state is unclear. Boulenouar et al. (2017) now report that heterogenous type 1 ILCs in adipose tissues regulate macrophage homeostasis through cytotoxicity.
From business to politics and sport to science, they’re the next generation talents putting Ireland on the map. Andrea smith rounds up 40 Irish people under 40, whose names you’ll want to drop.
At the coalface of groundbreaking scientific and health research all over the world are these eight pioneering women…
Lydia Lynch, PhD, of the Division of Endocrinology, was recently awarded a Junior Faculty Career Development Award from the American Diabetes Association (ADA) for her work investigating the positive role of iNKT cells in diabetes and obesity.
The Junior Faculty Career Development Award is given to new principal investigators working in the field of diabetes and provides scientists with $550,000 in funding over four years to continue their work researching the disease.
Prof Lydia Lynch has secured ERC funding to look at how immune cells can tackle obesity and diabetes.
Researchers at Harvard-affiliated Beth Israel Deaconess Medical Center (BIDMC) have found that a type of immune system cell once thought rare in humans is actually plentiful in fat cells and protects against obesity and the metabolic syndrome that leads to diabetes.