Single cell RNA-Seq

The Lynch Lab is now utilizing in-house single cell RNA-Seq analysis to drive and inform a number of different exciting projects, including identifying global changes in the immune system associated with obesity and weight loss, providing insights into innate T cell biology and innate T cell cellular metabolism, investigating the phenotype and functions of the unique adipose immune system, and studying innate T cell signatures in the context of cancer/tumor immunology. We also have ongoing collaborations with Dr Micheal Brenner and the single cell core in Harvard Medical School, as well as the Computer Science & Artificial Intelligence Lab at CSAIL, MIT.